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2003 Course Biomaterials (Elective II)

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Total No. of Questions : 12] P1390 [Total No. of Pages : 2 [3764]-463 B.E. (Biotechnology) BIOMATERIALS (416286) (2003 Course) (Elective - II) Time : 3 Hours] [Max. Marks : 100 Instructions to the candidates : 1) Answer any 3 questions from each section. 2) Answers to the two sections should be written in separate books. 3) Neat diagrams must be drawn wherever necessary. 4) Figures to the right indicate full marks. 5) All questions are compulsory. SECTION - I Q1) a) Explain general properties of materials that are useful for medicine applications? Explain different classes of materials used in medicine.[10] b) List out three important common properties to all metals which are being used during implants. [6] OR Q2) Explain in details alongwith properties and functions of: [16] a) b) c) d) Biological functional materials. Smart materials. Porous materials. Biodegradable materials. Q3) Explain structure, physical and chemical properties of polylactic acid? How method of synthesis differs from other common polymerization processes. With neat sketch detail out the synthesis procedure for the same. [16] OR Q4) a) Explain in detail fermentative production of polyesters like poly hydroxyalkonates. [10] b) Explain structure and properties of lactoyallatic acid, polycaprolactone. [6] Q5) How are shape memory alloys different from general metal alloys? Discuss their biomedical applications. [18] P.T.O. Q6) a) b) OR Explain mass spectrometer and atomic forced microscopy for analysis of polymer structure. Biomedical application of pulluan write a note. [18] SECTION - II Q7) Write a note on: a) Application of biocatalyst in biotransformation process. [16] b) c) d) L - homophenylanine production using membrane bioreactor. Biocompatible and bioinert materials. Ceramic and composite materials. OR Q8) Explain biocatalyst . How it works for production of polymer, aromatic precursors. Explain any one industrial application of biocatalyst with suitable example. [16] Q9) Separately list the type of materials used in each of the following medical applications alongwith feasibility of materials for said application. [16] a) c) Q10)a) b) Q11)a) b) Bone cement. Skin repair. b) Contact lenses. OR List out typical materials used in making lenses. List out problems observed after the replacement of heat valves. How can we use stress strain diagrams in selecting the most appropriate materials for an orthopedic biomaterials. [14] Hydrogel applications in medicine explain. [4] OR Q12)Write a note on (any two): a) Dental implants. c) DNA nanoparticles. [18] b) Y [3764]-463 [8] [8] 2 Polymer in Bioadhesives.

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