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GATE 2015 : Life Sciences [Section I]

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GATE 2015 BIOCHEMISTRY XL-I I : BIOCHEMISTRY Q. 1 Q. 10 carry one mark each. Q.1 Which one of the following small molecules is a prerequisite for fatty acid oxidation? (A) Inositol Q.2 (B) Choline (C) Carnitine (D) Glycerol Which one of the following bases is NOT found in the T-arm of an aminoacyl t-RNA? (A) Dihydrouridine (B) Pseudouridine (C) Uracil (D) Guanine Q.3 Oxidation of one molecule of glucose via the glycerol-phosphate shuttle produces (A) 32 molecules of ATP (C) 30 molecules of ATP Q.4 (B) 32 molecules of NADPH (D) 30 molecules of NADPH Ribulose-5-phosphate epimerase is involved in which one of the following processes? (A) Glycolysis (B) TCA cycle (C) Glycosylation (D) Pentose phosphate pathway Q.5 Proteolytic enzymes are usually biosynthesized as large, inactive precursors known as (A) holoenzymes (C) zymogens Q.6 The formation of a carbocation, also called an oxonium ion, occurs during the reaction catalyzed by (A) aldolase Q.7 (B) lysozyme (C) ribonuclease A (D) ) carboxypeptidase Which one of the following amino acid substitutions is likely to cause the largest change in protein conformation? (A) Phe Ile Q.8 (B) ribozyme (D) apoenzymes (B) Ser Thr (C) Gln Tyr (D) Glu Val Which one of the following does NOT constitute the lipid moiety in lipid-linked membrane proteins? (A) Palmitic acid (C) Farnesyl groups (B) Stearic acid (D) Myristic acid Q.9 A closed circular B-DNA of 4000 base pairs is negatively supercoiled by introduction of 4 writhes. The super helical density of the resultant DNA molecule will be _________ Q.10 Which one of the following is NOT a receptor tyrosine kinase? (A) Platelet derived growth factor receptor (B) Insulin like growth factor - 1 receptor (C) Macrophage colony stimulating factor receptor (D) Transforming growth factor receptor XL-I 1/5

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