Trending ▼   ResFinder  

Pune University - Molecular Biology - I, April 2010

2 pages, 16 questions, 0 questions with responses, 0 total responses,    0    0
pune_sci
   		+Fave Message
ProfileTimelineUploadsQ & A
 Home > pune_sci >

Instantly get Model Answers to questions on this ResPaper. Try now!
NEW ResPaper Exclusive!

Formatting page ...

Total No. of Questions : 5] P1013 [Total No. of Pages : 2 [3725] - 302 M.Sc. MICROBIOLOGY MB - 702 : Molecular Biology - I (2008 Pattern) Time : 3 Hours] [Max. Marks : 80 Instructions to the candidates: 1) All questions are compulsory. 2) All questions carry equal marks. 3) Neat well labeled diagrams must be drawn wherever necessary. 4) Use of log tables and electronic pocket calculator is allowed. 5) Assume suitable data, if necessary. Q1) Attempt any two of the following : [16] a) How is the problem of linear replicons solved? b) How does phage DNA replicate? c) How is the super family of a gene developed? Explain with examples. Q2) Attempt any two of the following : a) How RecA protein involved in recombination? b) How Transcription coupled repair system works? c) [16] How DNA methylation controls gene imprinting? Q3) Comment on any two of the following : a) Tumor suppressor gene with reference to RB. b) Retrotransposons and cancer. c) [16] Different types of DNA damages. P.T.O. Q4) Write short notes on any four of the following : a) T7 DNA polymerase. b) Y-family DNA polymerases. c) NHEJ. d) Cot value. e) Src Kinase. [16] Q5) a) Mouse memory tumor virus (MMTV) is an oncogene retrovirus that cause breast cancer in mice when it integrates in to the genome. You want to know whether it carries its own oncogene or generates an oncogene upon integration. You isolate 26 different breast cancers from mice that were exposed to MMTV and determine the sites at which the retroviruses are integrated. In 18 of 26 tumors the viruses are found at a variety of sites that are all located within a 20 kb segment of the mouse genome. Upon closer examination of these 18 tumors, you find that an RNA is expressed from the region of the mouse genome near the integrated virus, but not from the corresponding region in normal mouse breast cells. Do these observations argue for MMTV carrying an oncogene or for it generating an oncogene upon integration? Explain your reasoning. [10] b) Human DNA contains 20%C on a molar basis. What are the mole percents of A, G and T? [6] vvvv [3725]-302 2

Formatting page ...

 

  Print intermediate debugging step

Show debugging info


 

Additional Info : M.Sc. MICROBIOLOGY, MB - 702 : Molecular Biology - I (2008 Pattern), Pune University
Tags : pune msc microbiology, msc microbiology pune question papers, Molecular Biology I, pune university exam papers, university of pune question papers, pune university science, pune university courses, bsc pune university, msc pune university, pune university solved question papers, pune university model question paper, pune university paper pattern, pune university syllabus, old question papers pune university  

© 2010 - 2025 ResPaper. Terms of ServiceContact Us Advertise with us

 

pune_sci chat