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Pune University - Molecular Biology, April 2010 (Old Course)

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Total No. of Questions : 8] P1273 [Total No. of Pages : 2 [3727-B]-61 M.Sc. BIOTECHNOLOGY BT-21 : Molecular Biology (Old) Time : 3 Hours] [Max. Marks : 80 Instructions to candidates: 1) Attempt a total of Five questions selecting at least two questions from each section. 2) Answers to the two sections must be written on separate answer books. 3) Neat diagrams must be drawn wherever necessary. 4) Figures to the right indicate full marks. SECTION - I Q1) Explain the organisation and structure of genome of a prokaryote. [16] Q2) Explain: [16] a) Repetitive sequences. b) Chloroplast genome organisation. Q3) Explain a model of DNA replication. Add a note on role of DNA polymerases. [16] Q4) Write explanatory notes on: a) Structure and mechanism of action of reverse transcriptase. b) [16] DNA damage. SECTION - II Q5) Explain the molecular mechanisms involved in transcription. Add a note on regulation of transcription. [16] P.T.O. 1 Q6) Give a concise account of post transcriptional processing and transport of RNA. [16] Q7) Explain the molecular basis of the development of plant embryo and its germination. [16] Q8) Write explanatory notes on: [16] a) Pattern regulation during flower development. b) Oncogenes. [3727-B]-61 2 -2-

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Additional Info : MSc BIOTECHNOLOGY, BT 21 : Molecular Biology (Old Course), Pune University
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